Tuesday, January 06, 2009

More on gym newbies

I wanted to follow up on my previous rant about New Year's resolutioners at the gym.

Having so many newbies around can be understandably annoying for regulars, who tend to view the gym as their own turf. I think we always need to be nice and welcoming to the newcomers, though. It's tough, especially since it's naturaly for us to feel somewhat territorial. Still, let's make the effort.

Not too hard, though. The gym really isn't the kind of place where serious people intend to socialize. In fact, it's often kinda annoying to have someone engage you in long conversation at the gym, especially when you're trying to concentrate on your workout. It can also be annoying to the people around you, especially if you're talking loudly.

So let's strike a balance. Be friendly to the newbies, but don't treat the place as though it were a venue for a gabfest.

Monday, January 05, 2009

Invasion of the New Year's Resolutioners

It's January, and my gym has been invaded by New Year's resolutioners. I was almost unable to find a parking spot at the gym due to the massive surge in attendance. Finding a spot was made even more difficult by the fact that some of these motorists clogged up the lanes by waiting and waiting and waiting for someone to pull out of their spot.... you know, as opposed to driving a little bit further to park elsewhere.

My cardio bootcamp class was overflowing with newbies. We were practically packed in there like sardines. Not a pleasant situation.

Please don't get me wrong. I have nothing against newbies; in fact, when they seem friendly, I like to meet them and introduce them to some of the regulars. I also routinely cheer them on when they need encouragement. It is very annoying, however, that they choose to come in droves right after the holidays. The gym simply isn't equipped to deal with these inflated numbers.

It's especially aggravating because you know that the vast majority of these folks aren't taking exercise seriously. How do we know this? Because if they were, they wouldn't be waiting around for January 1st to start getting into shape. This isn't just idle speculation, mind you. Rather, it's pretty obvious --- especially when you see how much attendance drops when February rolls around.

I'll say more about that later.

Sunday, January 04, 2009

Zooey

I just learned that Zooey Deschanel, one of my favorite actresses, is starring in the Jim Carrey vehicle, "Yes Man." I have no intention of watching the show, but I am tempted to do so due to Zooey.

Mind you, she has her moments of serious clunkiness, as evidenced in "Tin Man." She can be pretty darned good though, and she's a spectacular singer. Throaty and enchanting and absolutely wonderful to listen to.

Another great answer

Here's another great answer to the question of whether we should always use the scientific method in our daily activities.

To me that shows why we CAN NOT use the scientific method in our personal relations. Suppose I have a friend at work who's usually polite and helpful. Then one day I notice that she's being rude, ignoring her duties, and so forth. If I insist on judging the situation based only on observation and logical deduction, I would have to conclude that she's somehow turned into a bad person. However, I also have another option: I can have faith in this person. And that's a perfectly reasonable thing to do. Her change in behavior may be resulting from something I don't know about, such as an illness, a family crisis, or something else. It may be something that I never know about. Nobody can ever observe another person thoroughly enough to completely understand all of that person's motivations, emotions, reasons, and thoughts. Hence, forming judgments about people solely by observation and logical deduction cannot truly be enough.


Again, slightly paraphrased. He's right. Human beings are too complex to be treated to a facile application of the scientific method.

Saturday, January 03, 2009

Riptide!

This page reminded me of something... I so want to watch the second and third seasons of [em]Riptide[/em] on DVD. This was a great detective show from the 80s that was pretty darned funny at times. The humor was sometimes quite painful to watch, but it had a lot of genuinely amusing moments.

Unfortunately, Netflix is only carrying the first season on DVD. I'd love to watch the remaining seasons, but I don't want to spend money on the DVD sets.

Friday, January 02, 2009

Assay principles

More about the ELISA Spot assay:

The ELISPOT assay can be done with freshly isolated PBMC or with PBMC frozen by certain specifications. Specifically designed 96-well plates are coated with a cytokine-specific monoclonal antibody (e.g., IFN-). PBMC (or purified T cell subsets) are pipetted into the coated wells, and are cultured with the test antigen(s). Control wells contain either irrelevant antigen, or media alone. T cells that are specific for the test antigen when activated secrete molecules that are captured by the membrane-bound antibody (Figure 3).

Induction of maximal cytokine production typically requires 24 h (IFN-, IL-2 and IL-3, IL-10 and TNF or 48 h for IL-4 and IL-5). After the activation culture, the cells are discarded (or transferred for further characterization/propagation), and a labeled cytokine-specific secondary antibody is added. Subsequently the plate bound secondary antibody is visualized via an enzymatic reaction. When ELISPOT assays are optimized (as is the case for ImmunoSpot® assays) each color precipitation (“spot”) represents the footprint of a single cell’s cytokine secretion. Spot number denotes the accurate frequency of the antigen specific T cells among the plated cells, spot size and morphology providing additional information on the magnitude and kinetics of the cells’ secretory activity.

Thursday, January 01, 2009

Bravo to this guy

I love what this guy said regarding the profanity debate.

The reason you can't begin to understand is that you're misreading what I wrote. I said "swearing is a habit that lazy people *CAN* fall back on...".

This does not mean "lazy people ALWAYS swear."

This does not mean "all swearing is done by lazy people."

There is no prejudice, except in your mind. It's a very simple statement. If one doesn't want to take the time and effort to think of the right word (e.g., one is linguistically lazy), then swearing is an easy way out. Do you *really* disagree with that?

And, by the way, you said "People who swear do it because that's the way they've always done it; that's just how they talk." How is that not the definition of "habit"? How is that not "remotely similar" to my point?

Again, read the argument. Swearing *IS NOT* equal to lazy. Swearing is a tool for lazy people. It's also a tool for intelligent, erudite people who know just the right time and place for a good profanity, and they can make it really effective.

And some people use it as filler, like um, er, ah, and like. When someone says, "I f*ckin' went to the latest fuckin' Jean-Claude Van-f*ckin'-Damme movie at the f*ckin' theater night before f*ckin' last, but I was so f*cked up I can't f*ckin' remember the f*ckin' plot," the profanity adds nothing to the sentence (not even emphasis, because it's so overused). When such a sentence is uttered loudly in a public place I consider it rude, thoughtless, and obnoxious.



Mind you, I'm not trying to justify the use of profanity. I don't think we should use it. From a purely literary perspective though, I think this guy is exactly right.

Wednesday, December 31, 2008

Even more profanity stupidity

Here is one of the most idiotic things that I read in this discussion on swearing.

How can swearing be less accurate or whatever than the words they are replacing. How is "there was a lot of sh*t in his garage" any different from "there was a lot of stuff in his garage."? It's the same thing!


Does this guy really think that profanity cannot make a statement less accurate? This sounds like a knee-jerk rationalization to me. It's pretty obvious that using a more generic word does make the statement less accurate -- or more precisely, less specific. The two rephrasings certainly are NOT the same thing insofar as the precise meaning of the former is not as readily discerned.

As one guy responded,

You're assuming that the listener knows that "sht*=stuff" in the speaker's mind. Nothing in this phrasing automatically sugggests that, though. None of the verbiage tells you if the speaker is talking about stuff that's mildly annoying, stuff that utterly reprehensible, or just plain "stuff."

Again, I'm not arguing against the use of profanity. That's a whole nuther debate. I just think it's foolish to think that swear words are just as precise or accurate as the words they are intended to replace. They aren't, especially since the same bits of profanity are used in casual contexts, at times of mild annoyance, and in the depths of fury and hellfire.

Tuesday, December 30, 2008

Yet another excuse for using profanity

The following ridiculous claim was uttered in defense of using profanity.

If I don't understand what a Frenchman says to me, that means that I don't understand French, not that the Frenchman isn't being clear and effective.


One guy responded by saying,

Speaking French or a strong dialect isn't analogous to swearing in English. It's the use to which the language is put, not the language itself that counts here. Some confusion can arise when using swear words (and, indeed to many other imprecise iterations) because they often are used as 'blanket' words. 'Fuck you' is a imprecise blast, used with strong feeling to express distaste of a particular action. It would be more accurate to specify what caused that reaction. The precise response may be not as satisfying or be able to put across the strength of feeling, though.


Yet another person said,

That's a false analogy and you know it. We're not talking about situations wherein people are using unfamiliar words or grammar. Rather, we're talking about situations wherein words are used indiscriminately, thereby robbing them of their impact and the ability to accurately communicate shades of meaning and emotion.

The problem lies in the indiscriminate use of this language. If you routinely use the word "sh*t" to mean excrement, something detestable, and just plain stuff, then the word loses its impact. Far from enhancing accurate communication, it simply serves as a barrier.

This problem isn't merely limited to profanity, BTW. The problem exists even within polite language. For example, I knew a graduate student who routinely described software designs as "good." His use of the word may have been accurate, but it was imprecise. A more effective communicator would be more specific, describing the designs as elegant, or efficient, or perhaps highly maintainable. The descriptor "good" lacked those nuances of meaning, and its indiscriminate use only aggravated that problem.

That's why it's a cop-oput to say that profanity is an excellent means of communication. It's only advantageous if used sparingly. When used indiscriminately, it blurs the distinction between truly aggravating circumstances and minor annoyances -- or worse, the humdrum routines of life.

Monday, December 29, 2008

Obama coins? Commemorative plates?

They're shilling commemorative Barack Obama coins and plates on TV now. That's just insane.

Look, I don't care if you're a Democrat or a Republican, liberal or conservative. It's a colossally stupid move to engage in such wide-eyed adulation before the man even steps into office. Why not wait and see how well he performs before showering him with these types of accolades? That would just be prudent.

I'd say the same thing about anyone who gets elected to the Presidency. This is why I've always said that we should not erect public monuments or commemorative symbols to living politicians -- or at the very least, politicians who have not yet put in decently long terms.

Sunday, December 28, 2008

Excusing profanity

I'm amazed at the lengths that some people would go to do defend profanity. I will heartily agree that profanity can be useful in communicating anger or disgust (though I don't condone its use). However, when people insist that profanity is the most effective way to communicate the depths of one's anger, or even the only way to do so, then that's just absurd. It indicates a complete lack of imagination on their part.

Consider the following exchange I saw in which this topic was debated:

Alright. So you come back from the garage upset about all the stuff in it. How would you express your anger about the situation?


One could launch a litany of insults against whoever caused the mess, or whoever created the stuff. One could wish the longest and most painful of torments on these people, their parents, and their progeny. One could describe the way one wants these people to be hung by their entrails, run through with fiery hot pokers, and forced to consume their own vomit. The list goes on.

I daresay that would be a more effective -- and far less ambiguous -- way of communicating anger than to say "This is all a bunch of sh*t!"

In discussing the use of profanity to convey anger, you said, "What else can convey that meaning?" With all due respect, I daresay that if a person cannot thinks there is no other way to convey the depths of his anger, then this is a reflection of that person's limited imagination and linguistic skill rather than any fundamental limitation of the language itself.


Preach it!

Saturday, December 27, 2008

More on profanity

How about the following exchange regarding the use of profanity?

Really nothing conveys anger better than swearing.


I'm gonna have to disagree with you on those points. Since when did swearing become the ultimate means of expressing anger? If anything, I think it's the easiest way to do so -- not necessarily the most effective way. In fact, since a lot of people toss around the f-word and s-word at the drop of a hat, regardless of their emotional state, I'd say that makes profanity a decidedly less effective way of expressing anger.

Is profanity a good way to express anger? Certainly. Is it the best, the ultimate, the most effective way? Only for people who lack imagination.

Friday, December 26, 2008

Swearing gets really old

I like what somebody said about swearing and how tedious it gets to hear someone use profanity all the time:

My husband swears a lot and it's really getting old. S*t, d**n, *ss and an emphatic f**k (she dreamed!) don't bother me at all. But he CONSTANTLY uses f**ker, c**ks**ker and m*th*rf**ker. If you say c**ks**ker or m*th*rf**ker when you drop a piece of bread or burn your finger, you're tapped out. There really isn't much worse that you can say. What if you get hit by a car, or your house burns down, or someone shoots your dog? You've already used up the worst words. Believe me, I can swear like a trucker IF PROVOKED, but overusing curses just makes one sound unintelligent, like you can't think of a smart thing to say. It's like getting into a physical fight (unless you are in danger, someone is attacking you or a loved one, etc.) Gee, I really have nothing intelligent to say, I think I'll just punch this guy or say f**king c*cks**ker because my pills fell on the floor. When you swear a lot, you rob the words of their impact and you just sound like an impatient, short-fused ass. When you hear it every day, it gets old really fast.

Thursday, December 25, 2008

This is my Christmas post

This is my blog entry for Christmas Day. I'm actually entering it late, but I'm dating it to December 25th anyway. Merry Christmas!

Wednesday, December 24, 2008

Christmas Eve

I got to spend Christmas Eve with a delightful family. Sadly, some of the men in that family tend to be way too foul-mouthed. On top of that, I have really serious reservations about the guy that one of these ladies is dating. He's friendly enough, but he just doesn't seem like a quality guy. She could do much better if she really chose to.

Tuesday, December 23, 2008

Mythbusters

I liked the following comment that somebody made regarding the Discovery Channel's show, [em]Mythbusters[/em].

As far as I'm concerned, the show is good because it's one of the few where what they do is more important than how they look, what their personalities are, how smooth their dialogue is, whether they sexually desirable, whether they are cool, whether the production is slick etc. At it's peak, the show was near unique in that they showed the backroom stuff. They showed not just the slickly performed payoff at the end, but how they built their rig, the scale rigs they built to try out ideas, the fuckups, the deadends, the rigs that didn't work.

It broke out of the mould in which every show must be based slick showiness, to the exclusion of substance.

It is slowly falling back into the boring standard mould, and is getting less and less to my taste because of it.

Monday, December 22, 2008

I learned a new term

I learned a new scientific term recently: HPBMC. I was familiar with the PBMC acronym, which stands for "peripheral blood mononuclear cells." Well then, "human PBMC" is naturally abbreviated as HPBMC.

Some things should be pretty obvious. Heh.

Okay, okay. In the grand scheme of things, this is a pretty minor rant.

Sunday, December 21, 2008

Lousy website design

I saw this website which had a small "search" function box in its upper right-hand corner. In the same corner, it had the following message:

Use the site's "Search Engine" located on the upper right corner, to list all content by keywords.


The designers of this site clearly had no sense of style or function. Not a lot of common sense, either. Oh, and they could use a good proofreader.

Saturday, December 20, 2008

HBD, M.

Happy Birthday, Mother. Happy Birthday.

Friday, December 19, 2008

I don't want to write

I should be writing manuals tonight. I don't want to, though. I am so sick of writing.